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Germline-targeting immunogens guide bnAb development
Structure-guided protein design enables germline-targeting immunization strategies to generate broadly neutralizing antibodies against MPER, a region of the HIV envelope glycoprotein that is functionally important and highly conserved, but a challenging target for antibody responses.
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A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice
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Circadian control of tumor immunosuppression affects efficacy of immune checkpoint blockade
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Vaccination induces broadly neutralizing antibody precursors to HIV gp41
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Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R–STAT5B-driven neoplasms