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Neural induction: Historical views and application to pluripotent stem cells

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dc.contributor.author Sasai, Noriaki
dc.contributor.author Kadoya, Minori
dc.contributor.author Chen, Agnes Ong Lee
dc.date.accessioned 2020-12-25T02:48:12Z
dc.date.available 2020-12-25T02:48:12Z
dc.date.issued 2020-12-02
dc.identifier.uri http://hdl.handle.net/10061/14173
dc.description.abstract Embryonic stem (ES) cells are a useful experimental material to recapitulate the differentiation steps of early embryos, which are usually invisible and inaccessible from outside of the body, especially in mammals. ES cells have greatly facilitated the analyses of gene expression profiles and cell characteristics. In addition, understanding the mechanisms during neural differentiation is important for clinical purposes, such as developing new therapeutic methods or regenerative medicine. As neurons have very limited regenerative ability, neurodegenerative diseases are usually intractable, and patients suffer from the disease throughout their lifetimes. The functional cells generated from ES cells in vitro could replace degenerative areas by transplantation. ja_JP
dc.language.iso en ja_JP
dc.publisher Wiley ja_JP
dc.relation.isreplacedby https://onlinelibrary.wiley.com/doi/10.1111/dgd.12703 ja_JP
dc.rights This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/dgd.12703. This article is protected by copyright. All rights reserved ja_JP
dc.title Neural induction: Historical views and application to pluripotent stem cells ja_JP
dc.type.nii Journal Article ja_JP
dc.contributor.transcription ササイ, ノリアキ
dc.contributor.transcription カドヤ, ミノリ
dc.contributor.alternative 笹井, 紀明
dc.contributor.alternative 角谷, 美典
dc.textversion none ja_JP
dc.identifier.eissn 1440-169X
dc.identifier.jtitle Development, Growth & Differentiation ja_JP
dc.relation.doi 10.1111/dgd.12703 ja_JP
dc.identifier.NAIST-ID 74651969 ja_JP
dc.identifier.NAIST-ID 85622108 ja_JP
dc.relation.pmid 33289091 ja_JP

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