Overexpression of MSN2, which is the transcription factor gene in response to stress, is well-known to increase the tolerance of the yeast Saccharomyces cerevisiae cells to a wide variety of environmental stresses. Recent ...

The shapes of plant organs such as sepals are precise and reproducible, although the cells composing these organs are highly heterogeneous. We investigate the collective behavior of a shape deformation model with spatio-temporal ...

We previously showed that curcumin, a phytopolyphenol found in turmeric (Curcuma longa), targets a series of enzymes in the ROS metabolic pathway, induces irreversible growth arrest, and causes apoptosis. In this study, ...

Cilia, the hair-like protrusions that beat at high frequencies to propel a cell or move fluid around are composed of radially bundled doublet microtubules. In this study, we present a near-atomic resolution map of the ...

Dorsal-ventral pattern formation of the neural tube is regulated by temporal and spatial activities of extracellular signalling molecules. Sonic hedgehog (Shh) assigns ventral neural subtypes via activation of the Gli ...

Ankyrin-repeat domains (ARDs) are conserved in large numbers of proteins. ARDs are composed of various numbers of ankyrin repeats (ANKs). ARDs often adopt curved structures reminiscent of the Bin-Amphiphysin-Rvs (BAR) ...

Arabidopsis (Arabidopsis thaliana) floral meristems terminate after the carpel primordia arise. This is achieved through the temporal repression of WUSCHEL (WUS), which is essential for stem cell maintenance. At floral ...

The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner. The floor plate, located in the ventral-most region of the neural tube, ...

Shootin1はクラッチ分子として重合・脱重合を繰り返すアクチン線維と細胞接着分子を連結することで細胞と細胞外基質の間に牽引力を生み出す．さらに，この力の発生はシグナル伝達によって調節を受ける．本稿では，最近のShootin1の解析を通じて明らかとなりつつある神経細胞の極性形成，軸索ガイダンス，細胞移動そして新たな細胞内分子輸送機構アクチン波の分子メカニクスを解説する．

The Gap phases of the cell cycle are essential to perceive internal and external signals and control cell division and differentiation. However, our knowledge of molecular mechanisms underlying G2 progression in plants ...