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Browsing 先端科学技術研究科 / Graduate School of Science and Technology by Title

Browsing 先端科学技術研究科 / Graduate School of Science and Technology by Title

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  • 1 mm3-sized Optical Neural Stimulator based on CMOS Integrated Photovoltaic 
    Tokuda, Takashi; Ishizu, Takaaki; Haruta, Makito; Noda, Toshihiko; Sasagawa, Kiyotaka; Mohamad, Sawan; Ohta, Jun (AIP Publishing, 2018-04)
    In this work, we present a simple complementary metal-oxide semiconductor (CMOS)-controlled photovoltaic power-transfer platform that is suitable for very small (less than or equal to 1–2 mm) electronic devices such as ...
  • 2.8-Å crystal structure of Escherichia coli YidC revealing all core regions, including flexible C2 loop 
    Tanaka, Yoshiki; Tsukazaki, Tomoya (Elsevier, 2018-10-20)
    YidC/Alb3/Oxa1 family proteins are involved in the insertion and assembly of membrane proteins. The core five transmembrane regions of YidC, which are conserved in the protein family, form a positively charged cavity open ...
  • A chimeric mutant analysis in yeast cells suggests BiP independent regulation of the mammalian endoplasmic reticulum-stress sensor IRE1α 
    Mai, Thanh Chi; Munakata, Takeo; Tran, Duc Minh; Takagi, Hiroshi; Kimata, Yukio (公益社団法人日本農芸化学会, 2018-05-28)
    An endoplasmic reticulum (ER)-located transmembrane protein, Ire1, triggers cytoprotective events upon ER stress. Chimeric yeast Ire1 carrying the luminal domain of the mammalian major Ire1 paralogue IRE1α is upregulated ...
  • A cis‐acting bidirectional transcription switch controls sexual dimorphism in the liverwort 
    Hisanaga, Tetsuya; Okahashi, Keitaro; Yamaoka, Shohei; Kajiwara, Tomoaki; Nishihama, Ryuichi; Shimamura, Masaki; Yamato, Katsuyuki T; Bowman, John L; Kohchi, Takayuki; Nakajima, Keiji (EMBO press, 2019-01-04)
    Plant life cycles alternate between haploid gametophytes and diploid sporophytes. While regulatory factors determining male and female sexual morphologies have been identified for sporophytic reproductive organs, such as ...
  • A novel mechanism for nitrosative stress tolerance dependent on GTP cyclohydrolase II activity involved in riboflavin synthesis of yeast. 
    Khairul, Anam; Nasuno, Ryo; Takagi, Hiroshi (nature, 2020-04-07)
    The biological functions of nitric oxide (NO) depend on its concentration, and excessive levels of NO induce various harmful situations known as nitrosative stress. Therefore, organisms possess many kinds of strategies to ...
  • ABA inhibits root cell elongation through repressing the cytokinin signaling 
    Takatsuka, Hirotomo; Umeda, Masaaki (Taylor & Francis, 2019-02-09)
    Cell elongation, which plays an important role in root penetration into the soil, responds to a variety of environmental factors. A previous study demonstrated that abscisic acid, a phytohormone involved in stress responses, ...
  • Are Donation Badges Appealing?: A Case Study of Developer Responses to Eclipse Bug Reports 
    Nakasai, Keitaro; Hata, Hideaki; Matsumoto, Kenichi (IEEE, 2018-10-22)
    Eclipse, an open source software project, acknowledges its donors by presenting donation badges. However, the effect of this strategy is unknown. We found that donation badges are appealing for donors and organizers because ...
  • Automatic Quantitative Segmentation of Myotubes Reveals Single-cell Dynamics of S6 Kinase Activation 
    Inoue, Haruki; Kunida, Katsuyuki; Matsuda, Naoki; Hoshino, Daisuke; Wada, Takumi; Imamura, Hiromi; Noji, Hiroyuki; Kuroda, Shinya (日本細胞生物学会, 2018-08-31)
    Automatic cell segmentation is a powerful method for quantifying signaling dynamics at single-cell resolution in live cell fluorescence imaging. Segmentation methods for mononuclear and round shape cells have been developed ...
  • AutoSort：レガシーシステム分析のためのプログラミング言語の判定支援手法 
    Okada, Joji; Ishio, Takashi; Sakata, Yuji; Inoue, Katsuro (情報処理学会, 2018-06-15)
    レガシーなメインフレームシステムには，拡張子が存在せずプログラミング言語が不明なソースコードファイルが多数存在する．レガシーシステムを分析する際には各ソースコードファイルのプログラミング言語を判定する必要があるが，これを手作業で行うと多大な労力が必要となってしまう．本研究ではプログラミング言語の判定作業を支援するために，手作業で判定すべきファイルの代表をクラスタリングによって選出する手法を提案する．正確な判定を支援するため，提案手法はパ ...
  • Blind Watermarking for 3D Printed Objects by Locally Modifying Layer Thickness 
    Arnaud, Delmotte; Tanaka, Kenichiro; Kubo, Hiroyuki; Funatomi, Takuya; Mukaigawa, Yasuhiro (IEEE, 2019-12-25)
    We propose a new blind watermarking algorithm for three-dimensional (3D) printed objects that has applications in metadata embedding, robotic grasping, counterfeit prevention, and crime investigation. Our method can be ...
  • Categorization of endoplasmic reticulum stress as accumulation of unfolded proteins or membrane lipid aberrancy using yeast Ire1 mutants 
    Duc, Minh Tran; Takagi, Hiroshi; Kimata, Yukio (公益社団法人日本農芸化学会, 2018-10-13)
    Endoplasmic reticulum (ER)-located protein Ire1 triggers the unfolded protein response against ER-stressing stimuli, which are categorized as ER accumulation of unfolded proteins or membrane lipid-related aberrancy. Here ...
  • Chromatin-mediated feed-forward auxin biosynthesis in floral meristem determinacy 
    Yamaguchi, Nobutoshi; Huang, Jiangbo; Tatsumi, Yoshitaka; Abe, Masato; Sugano, Shigeo S.; Kojima, Mikiko; Takebayashi, Yumiko; Kiba, Takatoshi; Yokoyama, Ryusuke; Nishitani, Kazuhiko; Sakakibara, Hitoshi; Ito, Toshiro (Springer Nature, 2018-12-11)
    In flowering plants, the switch from floral stem cell maintenance to gynoecium (female structure) formation is a critical developmental transition for reproductive success. In Arabidopsis thaliana, AGAMOUS (AG) terminates ...
  • Codosseum: オープンなソフトウェア開発・分析支援 
    上村　, 恭平; 中才, 恵太朗; 大神, 勝也; 畑, 秀明; 一ノ瀬, 智浩; 松本, 健一; 飯田, 元 (日本ソフトウェア科学会, 2019-01-25)
    ソフトウェア工学において，ソフトウェア開発データを分析・可視化し，エビデンスに基づく意思決定を支援するソフトウェアアナリティクスが注目されている．分析や可視化の技術は多数提案されているが，独立して開発されているため，実務者や研究者にとって様々な技術を統一的に活用することは容易でない．そこで我々は，オープンなソフトウェア開発データを有用な形式で公開し，複数の可視化を提供するWebサービス，Codosseumを開発した．具体的には，現在，メ ...
  • Conferment of CO-Controlled Dimer–Monomer Transition Property to Thermostable Cytochrome c′ by Mutation in the Subunit–Subunit Interface 
    Yamanaka, Masaru; Nakayama, Ryoko; Fujii, Sotaro; Wakai, Satoshi; Sambongi, Yoshihiro; HIrota, Shun (Chemical Society of Japan, 2019-01-11)
    Cytochrome c′ (CP) is a gas-binding homo-dimeric heme protein. Mesophilic Allochromatium vinosum CP (AVCP) and thermophilic Hydrogenophilus thermoluteolus CP (PHCP) have high sequence and structure similarities. AVCP is ...
  • Construction of a Quadrangular Tetramer and a Cage-Like Hexamer from Three-Helix Bundle-Linked Fusion Proteins 
    Miyamoto, Takaaki; Hayashi, Yugo; Yoshida, Keito; Watanabe, Hiroki; Uchihashi, Takayuki; Yonezawa, Kento; Shimizu, Nobutaka; Kamikubo, Hironari; Hirota, Shun (American Chemical Society, 2019-05-17)
    Self-assembled protein nanostructures have gained interest, owing to their potential applications in biomaterials; however, successful design and construction of protein nanostructures are limited. Herein, we constructed ...
  • Construction of a Triangle‐Shaped Trimer and a Tetrahedron Using an α‐Helix‐Inserted Circular Permutant of Cytochrome c555 
    Nagao, Satoshi; Yamanaka, Masaru; Ueda, Ikki; Watanabe, Hiroki; Uchihashi, Takayuki; Shibata, Naoki; Higuchi, Yoshiki; Hirota, Shun (John Wiley & Sons, Ltd, 2018-04-16)
    Highly-ordered protein structures have gained interest for future uses for biomaterials. Herein, we constructed a building block protein (BBP) by the circular permutation of the hyperthermostable Aquifex aeolicus cytochrome ...
  • Cysteine SH and Glutamate COOH Contributions to [NiFe] Hydrogenase Proton Transfer Revealed by Highly Sensitive FTIR Spectroscopy 
    Tai, Hulin; Nishikawa, Koji; Higuchi, Yoshiki; Mao, Zong-wan; Hirota, Shun (John Wiley & Sons, Ltd, 2019-07-25)
    A [NiFe] hydrogenase (H2ase) is a proton‐coupled electron transfer enzyme that catalyses reversible H2 oxidation; however, its fundamental proton transfer pathway remains unknown. Herein, we observed the protonation of ...
  • Cytokinin signaling coordinates development of diverse organs in Marchantia polymorpha 
    Aki, Shoiri S.; Nishihama, Ryuichi; Kohchi, Takayuki; Umeda, Masaaki (Taylor & Francis, 2019-09-18)
    Cytokinins play an essential role in plant growth and development. A recent study showed that the cytokinin signaling pathway was conserved in the liverwort Marchantia polymorpha, and that it controlled gemma cup and rhizoid ...
  • Cytokinin Signaling Is Essential for Organ Formation in Marchantia polymorpha 
    Aki, Shiori; Mikami, Tatsuya; Naramoto, Satoshi; Nishihama, Ryuichi; Ishizaki, Kimitsune; Kojima, Mikiko; Takebayashi, Yumiko; Sakakibara, Hitoshi; Kyozuka, Junko; Kohchi, Takayuki; Umeda, Masaaki (Oxford University Press, 2019-05-28)
    Cytokinins are known to regulate various physiological events in plants. Cytokinin signaling is mediated by the phosphorelay system, one of the most ancient mechanisms controlling hormonal pathways in plants. The liverwort ...
  • Detection system of the intracellular nitric oxide in yeast by HPLC with a fluorescence detector 
    Nasuno, Ryo; Shino, Seiya; Yoshikawa, Yuki; Yoshioka, Natsuko; Sato, Yuichi; Kamiya, Kohei; Hiroshi, Takagi (Elsevier, 2020-06-01)
    Nitric oxide (NO) is an important signaling molecule involved in various biological phenomena in many organisms. The physiological functions and metabolism of NO in yeast, a unicellular microorganism, are still unknown, ...

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