Tsuchiya, Yuichi; Saito, Michiko; Kadokura, Hiroshi; Miyazaki, Jun-ichi; Tashiro, Fumi; Imagawa, Yusuke; Iwawaki, Takao; Kohno, Kenji
(Rockefeller University Press, 2018-03-05)
In mammalian pancreatic β cells, the IRE1α–XBP1 pathway is constitutively and highly activated under physiological conditions. To elucidate the precise role of this pathway, we constructed β cell–specific Ire1α conditional ...