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Browsing バイオサイエンス研究科 / Graduate School of Biological Sciences by Title

Browsing バイオサイエンス研究科 / Graduate School of Biological Sciences by Title

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  • Mai, Chi Thanh; Le, Quynh Giang; Ishiwata-Kimata, Yuki; Takagi, Hiroshi; Kohno, Kenji; Kimata, Yukio (Oxford University Press, 2018-03-01)
    Accumulation of unfolded secretory proteins in the endoplasmic reticulum (ER), namely ER stress, is hazardous to eukaryotic cells and promotes the unfolded protein response (UPR). Ire1 is an ER-located transmembrane protein ...
  • Yasuda, Shinsuke; Wada, Yuko; Kakizaki, Tomohiro; Tarutani, Yoshiaki; Miura-Uno, Eiko; Murase, Kohji; Fujii, Sota; Hioki, Tomoya; Shimoda, Taiki; Takada, Yoshinobu; Shiba, Hiroshi; Takasaki-Yasuda, Takeshi; Suzuki, Go; Watanabe, Masao; Takayama, Seiji (Macmillan Publishers Limited, 2016-12-22)
    In diploid organisms, phenotypic traits are often biased by effects known as Mendelian dominant–recessive interactions between inherited alleles. Phenotypic expression of SP11 alleles, which encodes the male determinants ...
  • Toriyama, Michinori; Sakumura, Yuichi; Shimada, Tadayuki; Ishii, Shin; Inagaki, Naoyuki (John Wiley & Sons, Ltd, 2010-07-27)
    Although there has been significant progress in understanding the molecular signals that change cell morphology, mechanisms that cells use to monitor their size and length to regulate their morphology remain elusive. ...
  • Yin, Ke; Ueda, Minako; Takagi, Hitomi; Kajihara, Takehiro; Sugamata Aki, Shiori; Nobusawa, Takashi; Umeda-Hara, Chikage; Umeda, Masaaki (Wiley/Blackwell (10.1111), 2014-08-27)
    Visualization of the spatiotemporal pattern of cell division is crucial to understand how multicellular organisms develop and how they modify their growth in response to varying environmental conditions. The mitotic cell ...
  • Takahashi, Naoki; Ogita, Nobuo; Takahashi, Tomonobu; Taniguchi, Shoji; Tanaka, Maho; Seki, Motoaki; Umeda, Masaaki (eLife Sciences Publications, Ltd, 2019-04-04)
    Cell cycle arrest is an active response to stresses that enables organisms to survive under fluctuating environmental conditions. While signalling pathways that inhibit cell cycle progression have been elucidated, the ...
  • Kono, Takunari; Mehrotra, Sandhya; Endo, Chikako; Kizu, Natsuko; Matsuda, Mami; Kimura, Hiroyuki; Mizohata, Eiichi; Inoue, Tsuyoshi; Hasunuma, Tomohisa; Yokota, Akiho; Matsumura, Hiroyoshi; Ashida, Hiroki (Springer Nature, 2017-01-13)
    Two enzymes are considered to be unique to the photosynthetic Calvin–Benson cycle: ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), responsible for CO2 fixation, and phosphoribulokinase (PRK). Some archaea possess ...
  • Katsuno, Hiroko; Toriyama, Michinori; Hosokawa, Yoichiroh; Mizuno, Kensaku; Ikeda, Kazushi; Sakumura, Yuichi; Inagaki, Naoyuki (Elsevier, 2015-07-16)
    Actin and actin-associated proteins migrate within various cell types. To uncover the mechanism of their migration, we analyzed actin waves, which translocate actin and actin-associated proteins along neuronal axons toward ...
  • Inagaki, Naoyuki; Katsuno, Hiroko (Cell Press, 2017-03-07)
    Actin filaments and associated proteins undergo wave-like movement in various cell types. Recent studies with cutting-edge analyses, including live-cell imaging, biophysical monitoring and manipulation, and mathematical ...
  • Koi, Satoshi; Hisanaga, Tetsuya; Sato, Katsutoshi; Shimamura, Masaki; Yamato, Katsuyuki T; Ishizaki, Kimitsune; Kohchi, Takayuki; Nakajima, Keiji (Elsevier, 2016-06-23)
    In contrast to animals, in which the germ cell lineage is established during embryogenesis, plant germ cells are generated in reproductive organs via reprogramming of somatic cells. The factors that control germ cell ...
  • Inaba, Takuya; Watanabe, Daisuke; Yoshiyama, Yoko; Tanaka, Koichi; Ogawa, Jun; Takagi, Hiroshi; Shimoi, Hitoshi; Shima, Jun (Springer Open, 2013-12-30)
    Bacterial contamination is known as a major cause of the reduction in ethanol yield during bioethanol production by Saccharomyces cerevisiae. Acetate is an effective agent for the prevention of bacterial contamination, but ...
  • Chen, Poyu; Takatsuka, Hirotomo; Takahashi, Naoki; Kurata, Rie; Fukao, Yoichiro; Kobayashi, Kosuke; Ito, Masaki; Umeda, Masaaki (Springer Nature, 2017-09-21)
    Inhibition of cell division is an active response to DNA damage that enables cells to maintain genome integrity. However, how DNA damage arrests the plant cell cycle is largely unknown. Here, we show that the repressor-type ...
  • Izuho Hatada; Masakazu Namihira; Sumiyo Morita; Mika Kimura; Takuro Horii; Kinichi Nakashima (Public Library of Science, 2008-09-11)
    Epigenetic changes are thought to lead to alterations in the property of cells, such as differentiation potential. Neural precursor cells (NPCs) differentiate only into neurons in the midgestational brain, yet they become ...
  • Yoshiyama, Kaoru O; Kobayashi, Junya; Ogita, Nobuo; Ueda, Minako; Kimura, Seisuke; Maki, Hisaji; Umeda, Masaaki (EMBO, 2013-08-02)
    Arabidopsis SOG1 (suppressor of gamma response 1) is a plant‐specific transcription factor that governs the DNA damage response. Here we report that SOG1 is phosphorylated in response to DNA damage, and that this phosphorylation ...
  • Kanda, Satoshi; Yanagitani, Kota; Yokota, Yukiko; Esaki, Yuta; Kohno, Kenji (National Academy of Sciences of the United States of America, 2016-09-20)
    Unconventional mRNA splicing on the endoplasmic reticulum (ER) membrane is the sole conserved mechanism in eukaryotes to transmit information regarding misfolded protein accumulation to the nucleus to activate the stress ...
  • Davidson, Alice E; Liskova, Petra; Evans, Cerys J; Dudakova, Lubica; Noskova, Lenka; Pontikos, Nikolas; Hartmannova, Hana; Hodanova, Katerina; Stranecky, Viktor; Kozmik, Zbynek; Levis, Hannah J; Idigo, Nwamaka; Sasai, Noriaki; Maher, Geoffrey J; Bellingham, James; Veli, Neyme; Ebenezer, Neil D; Cheetham, Michael E; Daniels, Julie T; Thaung, Caroline M.H; Jirsova, Katerina; Plagnol, Vincent; Filipec, Martin; Kmoch, Stanislav; Tuft, Stephen J; Hardcastle, Alison J (Cell Press, 2017-01-07)
    Congenital hereditary endothelial dystrophy 1 (CHED1) and posterior polymorphous corneal dystrophy 1 (PPCD1) are autosomal-dominant corneal endothelial dystrophies that have been genetically mapped to overlapping loci on ...
  • Ito, Jun; Fukaki, Hidehiro; Onoda, Makoto; Li, Lin; Li, Chuanyou; Tasaka, Masao; Furutani, Masahiko (National Academy of Sciences, 2016-05-23)
    Mediator is a multiprotein complex that integrates the signals from transcription factors binding to the promoter and transmits them to achieve gene transcription. The subunits of Mediator complex reside in four modules: ...
  • Jun Kohyama; Tsukasa Sanosaka; Akinori Tokunaga; Eriko Takatsuka; Keita Tsujimura; Hideyuki Okano; Kinichi Nakashima (Rockefeller University Press, 2010-04)
    Once they have differentiated, cells retain their individual character and repress genes that are specifically expressed in other cell lineages, but how alternative fate choice is restricted during and/or after differentiation ...
  • Iwano, Megumi; Ito, Kanae; Fujii, Sota; Kakita, Mitsuru; Asano-Shimosato, Hiroko; Igarashi, Motoko; Kaothien-Nakayama, Pulla; Entani, Tetsuyuki; Kanatani, Asaka; Takehisa, Masashi; Tanaka, Masaki; Komatsu, Kunihiko; Shiba, Hiroshi; Nagai, Takeharu; Miyawaki, Atsushi; Isogai, Akira; Takayama, Seiji (Nature Publishing Group, 2015-09-01)
    Self-incompatibility in the Brassicaceae is controlled by multiple haplotypes encoding the pollen ligand (S-locus protein 11, SP11, also known as S-locus cysteine-rich protein, SCR) and its stigmatic receptor (S-receptor ...
  • Matsui, Takaaki; Thitamadee, Siripong; Murata, Tomoko; Kakinuma, Hisaya; Nabetani, Takuji; Hirabayashi, Yoshio; Hirate, Yoshikazu; Okamoto, Hitoshi; Bessho, Yasumasa (National Academy of Science, 2011-06-14)
    The assembly of progenitor cells is a crucial step for organ formation during vertebrate development. Kupffer’s vesicle (KV) is a key organ required for the left-right asymmetric body plan in zebrafish, and is generated ...
  • Inagaki, Soichi; Umeda, Masaaki (Elsevier, 2011-11-01)
    The cell cycle is driven by the activity of cyclin-dependent kinase (CDK)–cyclin complexes. Therefore, internal and external signals converge on the regulation of CDK–cyclin activity to modulate cell proliferation in ...

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