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バイオサイエンス研究科 / Graduate School of Biological Sciences

バイオサイエンス研究科 / Graduate School of Biological Sciences

 

最新登録資料

  • Yamaguchi, Nobutoshi; Huang, Jiangbo; Xu, Yifeng; Tanoi, Keitaro; Ito, Toshiro (Springer Nature, 2017-10-24)
    To ensure successful plant reproduction and crop production, the spatial and temporal control of the termination of the floral meristem must be coordinated. In Arabidopsis, the timing of this termination is determined by ...
  • Chen, Poyu; Takatsuka, Hirotomo; Takahashi, Naoki; Kurata, Rie; Fukao, Yoichiro; Kobayashi, Kosuke; Ito, Masaki; Umeda, Masaaki (Springer Nature, 2017-09-21)
    Inhibition of cell division is an active response to DNA damage that enables cells to maintain genome integrity. However, how DNA damage arrests the plant cell cycle is largely unknown. Here, we show that the repressor-type ...
  • Sugahara, Hirosuke; Okai, Shinsaku; Odamaki, Toshitaka; Wong, Chyn B; Kato, Kumiko; Mitsuyama, Eri; Xiao, Jin-Zhong; Shinkura, Reiko (Frontiers Media S.A., 2017-09-12)
    Gut microbiota is known to change with aging; however, the underlying mechanisms have not been well elucidated. Immunoglobulin A (IgA) is the dominant class of antibody secreted by the intestinal mucosa, and are thought ...
  • Luehders, Kristin; Sasai, Noriaki; Davaapil, Hongorzul; Kurosawa-Yoshida, Maiko; Hiura, Hitoshi; Brah, Tara; Ohnuma, Shin-ichi (The Company of Biologists, 2015-10-06)
    Small leucine-rich repeat proteoglycan (SLRP) family proteins play important roles in a number of biological events. Here, we demonstrate that the SLRP family member Asporin (ASPN) plays a crucial role in the early stages ...
  • Kutejova, Eva; Sasai, Noriaki; Shah, Ankita; Gouti, Mina; Briscoe, James (Cell Press, 2016-03-10)
    In the vertebrate neural tube, a morphogen-induced transcriptional network produces multiple molecularly distinct progenitor domains, each generating different neuronal subtypes. Using an in vitro differentiation system, ...
  • Vacca, Barbara; Sanchez-Heras, Elena; Steed, Emily; Balda, Maria S; Ohnuma, Shin-Ichi; Sasai, Noriaki; Mayor, Roberto; Matter, Karl (The Company of Biologists, 2016-11-15)
    Ocular morphogenesis requires several signalling pathways controlling the expression of transcription factors and cell-cycle regulators. However, despite a well-known mechanism, the dialogue between those signals and factors ...
  • Chek, Min Fey; Kim, Sun-Yong; Mori, Tomoyuki; Arsad, Hasni; Samian, Mohammed Razip; Sudesh, Kumar; Hakoshima, Toshio (Macmillan Publishers Limited, part of Springer Nature., 2017-07-13)
    Polyhydroxyalkanoate (PHA) is a promising candidate for use as an alternative bioplastic to replace petroleum-based plastics. Our understanding of PHA synthase PhaC is poor due to the paucity of available three-dimensional ...
  • Inagaki, Naoyuki; Katsuno, Hiroko (Cell Press, 2017-03-07)
    Actin filaments and associated proteins undergo wave-like movement in various cell types. Recent studies with cutting-edge analyses, including live-cell imaging, biophysical monitoring and manipulation, and mathematical ...
  • Kawasaki, Takumi; Ito, Kosuke; Miyata, Haruhiko; Akira, Shizuo; Kawai, Taro (EMBO Press, 2017-05-22)
    Alveolar macrophages (AMs) are specialized tissue‐resident macrophages that orchestrate the immune responses to inhaled pathogens and maintain organ homeostasis of the lung. Dysregulation of AMs is associated with allergic ...
  • Ariga, Hirotaka; Katori, Taku; Tsuchimatsu, Takashi; Hirase, Taishi; Tajima, Yuri; Parker, Jane E; Alcazar, Ruben; Koornneef, Maarten; Hoekenga, Owen; Lipka, Alexander E.; Gore, Michael A.; Sakakibara, Hitoshi; Kojima, Mikiko; Kobayashi, Yuriko; Iuchi, Satoshi; Kobayashi, Masatomo; Shinozaki, Kazuo; Sakata, Yoichi; Hayashi, Takahisa; Saijo, Yusuke; Taji, Teruaki (2017-05-26)
    Osmotic stress caused by drought, salt or cold decreases plant fitness. Acquired stress tolerance defines the ability of plants to withstand stress following an initial exposure. We found previously that acquired osmotolerance ...
  • Furukawa, Arata; Yoshikaie, Kunihito; Mori, Takaharu; Mori, Hiroyuki; Morimoto, Yusuke V; Sugano, Yasunori; Iwaki, Shigehiro; Minamino, Tohru; Sugita, Yuji; Tanaka, Yoshiki; Tsukazaki, Tomoya (Cell Press, 2017-05-02)
    Protein secretion mediated by SecYEG translocon and SecA ATPase is enhanced by membrane-embedded SecDF by using proton motive force. A previous structural study of SecDF indicated that it comprises 12 transmembrane helices ...
  • Tatebe, Hisashi; Murayama, Shinichi; Yonekura, Toshiya; Hatano, Tomoyuki; Richter, David; Furuya, Tomomi; Kataoka, Saori; Furuita, Kyoko; Kojima, Chojiro; Shiozaki, Kazuhiro; Sonenberg, Nahum (eLife Sciences Publications, Ltd, 2017-03-07)
    The target of rapamycin (TOR) protein kinase forms multi-subunit TOR complex 1 (TORC1) and TOR complex 2 (TORC2), which exhibit distinct substrate specificities. Sin1 is one of the TORC2-specific subunit essential for ...
  • Murase, Kohji; Shigenobu, Shuji; Fujii, Sota; Ueda, Kazuki; Murata, Takanori; Sakamoto, Ai; Wada, Yuko; Yamaguchi, Katsushi; Osakabe, Yuriko; Osakabe, Keishi; Kanno, Akira; Ozaki, Yukio; Takayama, Seiji (John Wiley & Sons, Inc., 2017-01-12)
    Dioecy is a plant mating system in which individuals of a species are either male or female. Although many flowering plants evolved independently from hermaphroditism to dioecy, the molecular mechanism underlying this ...
  • Davidson, Alice E; Liskova, Petra; Evans, Cerys J; Dudakova, Lubica; Noskova, Lenka; Pontikos, Nikolas; Hartmannova, Hana; Hodanova, Katerina; Stranecky, Viktor; Kozmik, Zbynek; Levis, Hannah J; Idigo, Nwamaka; Sasai, Noriaki; Maher, Geoffrey J; Bellingham, James; Veli, Neyme; Ebenezer, Neil D; Cheetham, Michael E; Daniels, Julie T; Thaung, Caroline M.H; Jirsova, Katerina; Plagnol, Vincent; Filipec, Martin; Kmoch, Stanislav; Tuft, Stephen J; Hardcastle, Alison J (Cell Press, 2017-01-07)
    Congenital hereditary endothelial dystrophy 1 (CHED1) and posterior polymorphous corneal dystrophy 1 (PPCD1) are autosomal-dominant corneal endothelial dystrophies that have been genetically mapped to overlapping loci on ...
  • Kono, Takunari; Mehrotra, Sandhya; Endo, Chikako; Kizu, Natsuko; Matsuda, Mami; Kimura, Hiroyuki; Mizohata, Eiichi; Inoue, Tsuyoshi; Hasunuma, Tomohisa; Yokota, Akiho; Matsumura, Hiroyoshi; Ashida, Hiroki (Springer Nature, 2017-01-13)
    Two enzymes are considered to be unique to the photosynthetic Calvin–Benson cycle: ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), responsible for CO2 fixation, and phosphoribulokinase (PRK). Some archaea possess ...
  • Yasuda, Shinsuke; Wada, Yuko; Kakizaki, Tomohiro; Tarutani, Yoshiaki; Miura-Uno, Eiko; Murase, Kohji; Fujii, Sota; Hioki, Tomoya; Shimoda, Taiki; Takada, Yoshinobu; Shiba, Hiroshi; Takasaki-Yasuda, Takeshi; Suzuki, Go; Watanabe, Masao; Takayama, Seiji (Macmillan Publishers Limited, 2016-12-22)
    In diploid organisms, phenotypic traits are often biased by effects known as Mendelian dominant–recessive interactions between inherited alleles. Phenotypic expression of SP11 alleles, which encodes the male determinants ...
  • Yamada, Kohji; Saijo, Yusuke; Nakagami, Hirofumi; Takano, Yoshitaka (American Association for the Advancement of Science, 2016-11-24)
    Microbial pathogens strategically acquire metabolites from their hosts during infection. Here we show that the host can intervene to prevent such metabolite loss to pathogens. Phosphorylation-dependent regulation of sugar ...
  • Kamiya, Masako; Higashio, Shin-Ya; Isomoto, Atsushi; Kim, Jong-Myong; Seki, Motoaki; Miyashima, Shunsuke; Nakajima, Keiji (The Company of Biologists Ltd, 2016-11-01)
    The root cap supports root growth by protecting the root meristem, sensing gravity and interacting with the rhizosphere through metabolite secretion and cell dispersal. Sustained root cap functions therefore rely on balanced ...
  • Okubo-Kurihara, Emiko; Ohtani, Misato; Kurihara, Yukio; Kakegawa, Koichi; Kobayashi, Megumi; Nagata, Noriko; Komatsu, Takanori; Kikuchi, Jun; Cutler, Sean; Demura, Taku; Matsui, Minami (Macmillan Publishers Limited, part of Springer Nature, 2016-10-03)
    The cell wall is one major determinant of plant cell morphology, and is an attractive bioresource. Here, we report a novel strategy to modify plant cell wall property by small molecules. Lasalocid sodium (LS) was isolated ...
  • Kanda, Satoshi; Yanagitani, Kota; Yokota, Yukiko; Esaki, Yuta; Kohno, Kenji (National Academy of Sciences of the United States of America, 2016-09-20)
    Unconventional mRNA splicing on the endoplasmic reticulum (ER) membrane is the sole conserved mechanism in eukaryotes to transmit information regarding misfolded protein accumulation to the nucleus to activate the stress ...

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