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学術雑誌論文 / Journal Article

学術雑誌論文 / Journal Article

Recent Submissions

  • Aoki, Wataru; Saito, Masato; Manabe, Ri-ichiroh; Mori, Hirotada; Yamaguchi, Yoshinori; Tamiya, Eiichi (Nature Publishing Group, 2014-04-17)
    We propose ‘integrated synthetic genetics’ as a novel methodology that integrates reductive and synthetic approaches used in life science research. Integrated synthetic genetics enables determinations of sets of genes ...
  • Montero, Manuel; Rahimpour, Mehdi; Viale, Alejandro M.; Almagro, Goizeder; Eydallin, Gustavo; Sevilla, Angel; Canovas, Manuel; Bernal, Cristina; Lozano, Ana Belen; Munoz, Francisco Jose; Baroja-Fernandez, Edurne; Bahaji, Abdellatif; Mori, Hirotada; Codoner, Francisco M.; Pozueta-Romero, Javier (Public Library of Science, 2014-09-04)
    In Escherichia coli, ppGpp is a major determinant of growth and glycogen accumulation. Levels of this signaling nucleotide are controlled by the balanced activities of the ppGpp RelA synthetase and the dual-function ...
  • Yamamoto, Tatsuo; Takano, Tomomi; Higuchi, Wataru; Iwao, Yasuhisa; Singur, Olga; Reva, Ivan; Otsuka, Yuta; Nakayashiki, Toru; Mori, Hirotada; Reva, Galina; Kuznetsov, Vladimir; Potapov, Vladimir (Public Library of Science, 2012-01-19)
    Two distinct classes of methicillin-resistant Staphylococcus aureus (MRSA) are spreading in hospitals (as hospital-acquired MRSA, HA-MRSA) and in the community (as community-acquired MRSA, CA-MRSA). Multilocus sequence ...
  • Rajagopala, Seesandra V; Titz, Bjorn; Goll, Johannes; Parrish, Jodi R; Wohlbold, Katrin; McKevitt, Matthew T; Palzkill, Timothy; Mori, Hirotada; Finley, Russell L; Uetz, Peter (Nature Publishing Group, 2007-07-31)
    Motility is achieved in most bacterial species by the flagellar apparatus. It consists of dozens of different proteins with thousands of individual subunits. The published literature about bacterial chemotaxis and flagella ...
  • Usui, Yuki; Hirasawa, Takashi; Furusawa, Chikara; Shirai, Tomokazu; Yamamoto, Natsuko; Mori, Hirotada; Shimizu, Hiroshi (BioMed Central Ltd, 2012-06-21)
    It has long been recognized that analyzing the behaviour of the complex intracellular biological networks is important for breeding industrially useful microorganisms. However, because of the complexity of these biological ...
  • Tian, Zhongyuan; Faure, Adrien; Mori, Hirotada; Matsuno, Hiroshi (BioMed Central Ltd, 2013-12-13)
    Glycogen and glucose are two sugar sources available during the lag phase of E. coli, but the mechanism that regulates their utilization is still unclear.
  • Yamamoto, Natsuko; Nakahigashi, Kenji; Nakamichi, Tomoko; Yoshino, Mihoko; Takai, Yuki; Touda, Yae; Furubayashi, Akemi; Kinjyo, Satoko; Dose, Hitomi; Hasegawa, Miki; Datsenko, Kirill A; Nakayashiki, Toru; Tomita, Masaru; Wanner, Barry L; Mori, Hirotada (Nature Publishing Group, 2009-12-22)
    The Keio collection (Baba et al, 2006) has been established as a set of single‐gene deletion mutants of Escherichia coli K‐12. These mutants have a precisely designed deletion from the second codon from the seventh to the ...
  • Nakahigashi, Kenji; Toya, Yoshihiro; Ishii, Nobuyoshi; Soga, Tomoyoshi; Hasegawa, Miki; Watanabe, Hisami; Takai, Yuki; Honma, Masayuki; Mori, Hirotada; Tomita, Masaru (Nature Publishing Group, 2009-09-15)
    Central carbon metabolism is a basic and exhaustively analyzed pathway. However, the intrinsic robustness of the pathway might still conceal uncharacterized reactions. To test this hypothesis, we constructed systematic ...
  • Otsuka, Yuta; Muto, Ai; Takeuchi, Rikiya; Okada, Chihiro; Ishikawa, Motokazu; Nakamura, Koichiro; Yamamoto, Natsuko; Dose, Hitomi; Nakahigashi, Kenji; Tanishima, Shigeki; Suharnan, Sivasundaram; Nomura, Wataru; Nakayashiki, Toru; Aref, Walid G.; Bochner, Barry R.; Conway, Tyrrell; Gribskov, Michael; Kihara, Daisuke; Rudd, Kenneth E.; Tohsato, Yukako; Wanner, Barry L.; Mori, Hirotada (Oxford University Press, 2015-01-28)
    Comprehensive experimental resources, such as ORFeome clone libraries and deletion mutant collections, are fundamental tools for elucidation of gene function. Data sets by omics analysis using these resources provide key ...
  • Takeuchi, Rikiya; Tamura, Takeyuki; Nakayashiki, Toru; Tanaka, Yuichirou; Muto, Ai; Wanner, Barry L.; Mori, Hirotada (BioMed Central Ltd, 2014-06-26)
    Precise quantitative growth measurements and detection of small growth changes in high-throughput manner is essential for fundamental studies of bacterial cell. However, an inherent tradeoff for measurement quality in ...
  • Nakahigashi, Kenji; Takai, Yuki; Shiwa, Yuh; Wada, Mei; Honma, Masayuki; Yoshikawa, Hirofumi; Tomita, Masaru; Kanai, Akio; Mori, Hirotada (BioMed Central Ltd, 2014-12-16)
    There is a significant difference between synonymous codon usage in many organisms, and it is known that codons used more frequently generally showed efficient decoding rate. At the gene level, however, there are conflicting ...
  • Shinhara, Atsuko; Matsui, Motomu; Hiraoka, Kiriko; Nomura, Wataru; Hirano, Reiko; Nakahigashi, Kenji; Tomita, Masaru; Mori, Hirotada; Kanai, Akio (BioMed Central Ltd, 2011-08-24)
    In Escherichia coli, approximately 100 regulatory small RNAs (sRNAs) have been identified experimentally and many more have been predicted by various methods. To provide a comprehensive overview of sRNAs, we analysed the ...
  • Khan, Ishita; Chen, Yuqian; Dong, Tiange; Hong, Xioawei; Takeuchi, Rikiya; Mori, Hirotada; Kihara, Daisuke (BioMed Central Ltd, 2014-12-11)
    Moonlighting proteins perform two or more cellular functions, which are selected based on various contexts including the cell type they are expressed, their oligomerization status, and the binding of different ligands at ...
  • CRMP 
    久保, 祐亮; 稲垣, 直之 (理化学研究所 脳科学総合研究センター, 2012-10-26)
    コラプシン反応媒介タンパク質(collapsin response mediator proteins, CRMPs)は、軸索の反発性因子であるセマフォリン3A(Sema3A)の細胞内シグナルを伝達する分子として最初に同定された。CRMPsは、細胞質タンパク質であり、これまでに5つのサブタイプ(CRMP1~5)が同定されている。これらの発現は主に発生時期の神経系に認められ、それぞれ特異的な発現分布と発現時期を示す。CRMPsは線虫Unc ...
  • 馬場, 健太郎; 浦崎, 明宏; 稲垣, 直之 (日本電気泳動学会, 2014-10-31)
  • Toriyama, Michinori; Sakumura, Yuichi; Shimada, Tadayuki; Ishii, Shin; Inagaki, Naoyuki (John Wiley & Sons, Ltd, 2010-07-27)
    Although there has been significant progress in understanding the molecular signals that change cell morphology, mechanisms that cells use to monitor their size and length to regulate their morphology remain elusive. ...
  • Toriyama, Michinori; Shimada, Tadayuki; Kim, Ki Bum; Mitsuba, Mari; Nomura, Eiko; Katsuta, Kazuhiro; Sakumura, Yuichi; Roepstorff, Peter; Inagaki, Naoyuki (The Rockefeller University Press, 2006-10-09)
    Neurons have the remarkable ability to polarize even in symmetrical in vitro environments. Although recent studies have shown that asymmetric intracellular signals can induce neuronal polarization, it remains unclear how ...
  • Mori, Tatsuya; Wada, Tomoe; Suzuki, Takahiro; Kubota, Yoshitsugu; Inagaki, Naoyuki (American Society for Biochemistry and Molecular Biology, 2007-07-06)
    Although neuronal functions depend on their robust polarity, the mechanisms that ensure generation and maintenance of only a single axon remain poorly understood. Using highly sensitive two-dimensional electrophoresis-based ...
  • Shimada, Tadayuki; Toriyama, Michinori; Uemura, Kaori; Kamiguchi, Hiroyuki; Sugiura, Tadao; Watanabe, Naoki; Inagaki, Naoyuki (The Rockefeller University Press, 2008-06-02)
    Actin polymerizes near the leading edge of nerve growth cones, and actin filaments show retrograde movement in filopodia and lamellipodia. Linkage between actin filament retrograde flow and cell adhesion molecules (CAMs) ...
  • Inagaki, Naoyuki; Toriyama, Michinori; Sakumura, Yuichi (Wiley Subscription Services, Inc., A Wiley Company, 2011-05-06)
    Polarization, in which a single axon and multiple dendrites are formed, is crucial for neuronal functions, and symmetry breaking is the initial step of this process. Accumulating studies have revealed a number of molecules ...

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