• ABA inhibits root cell elongation through repressing the cytokinin signaling 

  Takatsuka, Hirotomo; Umeda, Masaaki (Taylor & Francis, 2019-02-09)

  Cell elongation, which plays an important role in root penetration into the soil, responds to a variety of environmental factors. A previous study demonstrated that abscisic acid, a phytohormone involved in stress responses, ...
• Cytokinin signaling coordinates development of diverse organs in Marchantia polymorpha 

  Aki, Shoiri S.; Nishihama, Ryuichi; Kohchi, Takayuki; Umeda, Ｍａｓａａｋｉ (Taylor & Francis, 2019-09-18)

  Cytokinins play an essential role in plant growth and development. A recent study showed that the cytokinin signaling pathway was conserved in the liverwort Marchantia polymorpha, and that it controlled gemma cup and rhizoid ...
• Gap 2 phase: making the fundamental decision to divide or not 

  Umeda, Masaak; Shiori S, Aki; Naoki, Takahashi (Elsevier, 2019-04-05)

  The Gap phases of the cell cycle are essential to perceive internal and external signals and control cell division and differentiation. However, our knowledge of molecular mechanisms underlying G2 progression in plants ...
• Oligomerization of cytochrome c, myoglobin, and related heme proteins by 3D domain swapping 

  Hirota, Shun (Elsevier, 2019-05)

  Oligomerization of heme proteins is useful for construction of new materials with cooperative and systematic functions; thus, diverse methods have been applied for construction of artificial heme protein oligomers. ...
• Protein surface charge effect on 3D domain swapping in cells for c-type cytochromes 

  Yang, Hongxu; Yamanaka, Masaru; Nagao, Satoshi; Yasuhara, Kazuma; Shibata, Naoki; Higuchi, Yoshiki; Hirota, Shun (Elsevier, 2019-11-01)

  Many c-type cytochromes (cyts) can form domain-swapped oligomers. The positively charged Hydrogenobacter thermophilus (HT) cytochrome (cyt) c552 forms domain-swapped oligomers during expression in the Escherichia coli ...
• Determination of proton concentration at cardiolipin-containing membrane interfaces and its relation with the peroxidase activity of cytochrome c† 

  Parui, Partha Pratim; Sarakar, Yeasmin; Majumder, Rini; Das, Sanju; Yang, Hongxu; Yasuhara, Kazuma; Hirota, Shun (Royal Society of Chemistry, 2019-08-06)

  The activities of biomolecules are affected by the proton concentrations at biological membranes. Here, we succeeded in evaluating the interface proton concentration (−log[H+] defined as pH′) of cardiolipin (CL)-enriched ...
• 着桟支援のためのGNSS搬送波位相とIMUの密結合と視覚オドメトリの融合による位置推定のロバスト化 

  中村, 拓; 園部, 達也; 戸田, 裕行; 藤澤, 奈緒美; 武富, 貴史; プロプスキ, アレクサンダー; サンドア, クリスチャン; 加藤, 博一 (一般社団法人 測位航法学会, 2019)

  船舶の着桟支援を想定したロバストな高精度測位手法を開発した．本手法は，自船に固定したカメラで撮影した動画像データ，複数のGNSSアンテナから受信した民生用L1信号データ，及び，6軸IMUデータの融合により実現する．動画像データの視覚オドメトリを用いて，港湾構造物の3次元構造を復元しつつ，6軸IMUデータとGNSS衛星単位の搬送波位相の時空間変化量とのタイトカップリングによって高精度に自船の軌跡を推定する新しいオドメトリ技術を構築した．さ ...
• Conferment of CO-Controlled Dimer–Monomer Transition Property to Thermostable Cytochrome c′ by Mutation in the Subunit–Subunit Interface 

  Yamanaka, Masaru; Nakayama, Ryoko; Fujii, Sotaro; Wakai, Satoshi; Sambongi, Yoshihiro; HIrota, Shun (Chemical Society of Japan, 2019-01-11)

  Cytochrome c′ (CP) is a gas-binding homo-dimeric heme protein. Mesophilic Allochromatium vinosum CP (AVCP) and thermophilic Hydrogenophilus thermoluteolus CP (PHCP) have high sequence and structure similarities. AVCP is ...
• Construction of a Triangle‐Shaped Trimer and a Tetrahedron Using an α‐Helix‐Inserted Circular Permutant of Cytochrome c555 

  Nagao, Satoshi; Yamanaka, Masaru; Ueda, Ikki; Watanabe, Hiroki; Uchihashi, Takayuki; Shibata, Naoki; Higuchi, Yoshiki; Hirota, Shun (John Wiley & Sons, Ltd, 2018-04-16)

  Highly-ordered protein structures have gained interest for future uses for biomaterials. Herein, we constructed a building block protein (BBP) by the circular permutation of the hyperthermostable Aquifex aeolicus cytochrome ...
• Oxidative modification of methionine80 in cytochrome c by reaction with peroxides 

  Nugraheni, Ari Dw; Ren, Chunguang; Matsumoto, Yorifumi; Nagao, Satoshi; Yamanaka, Masaru; Hirota, Shun (Elsevier, 2018-05-01)

  The Met80–heme iron bond of cytochrome c (cyt c) is cleaved by the interaction of cyt c with cardiolipin (CL) in membranes. The Met80 dissociation enhances the peroxidase activity of cyt c and triggers cyt c release from ...
• Integration of transcriptional repression and Polycomb-mediated silencing of WUSCHEL in floral meristems 

  Bo, Sun; Zhou, Yingying; Cai, Jie; Shang, Erlei; Yamaguchi, Nobutoshi; Xiao, Jun; Looi, Liang-Sheng; Wee, Wan-Yi; Gao, Xiuying; Wagner, Doris; Ito, Toshiro (AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS, 2019-07-01)

  Arabidopsis (Arabidopsis thaliana) floral meristems terminate after the carpel primordia arise. This is achieved through the temporal repression of WUSCHEL (WUS), which is essential for stem cell maintenance. At floral ...
• Cysteine SH and Glutamate COOH Contributions to [NiFe] Hydrogenase Proton Transfer Revealed by Highly Sensitive FTIR Spectroscopy 

  Tai, Hulin; Nishikawa, Koji; Higuchi, Yoshiki; Mao, Zong-wan; Hirota, Shun (John Wiley & Sons, Ltd, 2019-07-25)

  A [NiFe] hydrogenase (H2ase) is a proton‐coupled electron transfer enzyme that catalyses reversible H2 oxidation; however, its fundamental proton transfer pathway remains unknown. Herein, we observed the protonation of ...
• Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins 

  Ichikawa, Muneyoshi; Khalifa, Ahmad Abdelzaher Zaki; Kubo, Shintaroh; Dai, Daniel; Basu, Kaustuv; Maghrebi, Mohammad Amin Faghfor; Vargas, Javier; Bui, Khanh Huy (National Academy of Sciences, 2019-09-16)

  Cilia, the hair-like protrusions that beat at high frequencies to propel a cell or move fluid around are composed of radially bundled doublet microtubules. In this study, we present a near-atomic resolution map of the ...
• Membrane-deformation ability of ANKHD1 is involved in the early endosome enlargement 

  Kitamata, Manabu; Hanawa-Suetsugu, Kyoko; Maruyama, Kohei; Suetsugu, Shiro (Elsevier (Cell Press), 2019-07-26)

  Ankyrin-repeat domains (ARDs) are conserved in large numbers of proteins. ARDs are composed of various numbers of ankyrin repeats (ANKs). ARDs often adopt curved structures reminiscent of the Bin-Amphiphysin-Rvs (BAR) ...
• Effect of Coulomb Interaction and Disorder on Density of States in Conventional Superconductors 

  Jujo, Takanobu (The Physical Society of Japan, 2019-09-03)

  The density of states of the disordered s-wave superconductor is calculated perturbatively. The effect of Coulomb interaction on diffusively moving electrons in the normal state has been known before, but in the superconducting ...
• Structural Basis of the Sec Translocon and YidC Revealed Through X-ray Crystallography 

  Tsukazaki, Tomoya (Springer US, 2019-04)
• RNF152 Negatively Regulates mTOR Signalling and Blocks Cell Proliferation in the Floor Plate 

  Kadoya, Minori; Sasai, Noriaki (Cold Spring Harbor Laboratory, 2019-05-23)

  The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner. The floor plate, located in the ventral-most region of the neural tube, ...
• GPR17 is an essential regulator for the temporal adaptation of Sonic hedgehog signalling in neural tube development 

  Yatsuzuka, Atsuki; Hori, Akiko; Kadoya, Minori; Matsuo-Takasaki, Mami; Kondo, Toru; Sasai, Noriaki (Company of Biologists: Development, 2019-08-23)

  Dorsal-ventral pattern formation of the neural tube is regulated by temporal and spatial activities of extracellular signalling molecules. Sonic hedgehog (Shh) assigns ventral neural subtypes via activation of the Gli ...
• Handheld Guides in Inspection Tasks: Augmented Reality versus Picture 

  Polvi, Jarkko; Taketomi, Takafumi; Moteki, Atsunori; Yoshitake, Toshiyuki; Fukuoka, Toshiyuki; Yamamoto, Goshiro; Sandor, Christian; Kato, Hirokazu (IEEE, 2018-07-01)

  Inspection tasks focus on observation of the environment and are required in many industrial domains. Inspectors usually execute these tasks by using a guide such as a paper manual, and directly observing the environment. ...
• Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system 

  Urasaki, Akihiro; Morishita, Seiya; Naka, Kosuke; Uozumi, Minato; Abe, Kouki; Huang, Liguo; Watase, Emiko; Nakagawa, Osamu; Kawakami, Koichi; Matsui, Takaaki; Bessho, Yasumasa; Inagaki, Naoyuki (Springer Nature, 2019-08-21)

  The zebrafish sensory posterior lateral line is an excellent model system to study collective cell migration and organogenesis. Shootin1 is a cytoplasmic protein involved in neuronal polarization and axon guidance. Previous ...

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