• Cysteine SH and Glutamate COOH Contributions to [NiFe] Hydrogenase Proton Transfer Revealed by Highly Sensitive FTIR Spectroscopy 

  Tai, Hulin; Nishikawa, Koji; Higuchi, Yoshiki; Mao, Zong-wan; Hirota, Shun (John Wiley & Sons, Ltd, 2019-07-25)

  A [NiFe] hydrogenase (H2ase) is a proton‐coupled electron transfer enzyme that catalyses reversible H2 oxidation; however, its fundamental proton transfer pathway remains unknown. Herein, we observed the protonation of ...
• Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins 

  Ichikawa, Muneyoshi; Khalifa, Ahmad Abdelzaher Zaki; Kubo, Shintaroh; Dai, Daniel; Basu, Kaustuv; Maghrebi, Mohammad Amin Faghfor; Vargas, Javier; Bui, Khanh Huy (National Academy of Sciences, 2019-09-16)

  Cilia, the hair-like protrusions that beat at high frequencies to propel a cell or move fluid around are composed of radially bundled doublet microtubules. In this study, we present a near-atomic resolution map of the ...
• Membrane-deformation ability of ANKHD1 is involved in the early endosome enlargement 

  Kitamata, Manabu; Hanawa-Suetsugu, Kyoko; Maruyama, Kohei; Suetsugu, Shiro (Elsevier (Cell Press), 2019-07-26)

  Ankyrin-repeat domains (ARDs) are conserved in large numbers of proteins. ARDs are composed of various numbers of ankyrin repeats (ANKs). ARDs often adopt curved structures reminiscent of the Bin-Amphiphysin-Rvs (BAR) ...
• Effect of Coulomb Interaction and Disorder on Density of States in Conventional Superconductors 

  Jujo, Takanobu (The Physical Society of Japan, 2019-09-03)

  The density of states of the disordered s-wave superconductor is calculated perturbatively. The effect of Coulomb interaction on diffusively moving electrons in the normal state has been known before, but in the superconducting ...
• Structural Basis of the Sec Translocon and YidC Revealed Through X-ray Crystallography 

  Tsukazaki, Tomoya (Springer US, 2019-04)
• RNF152 Negatively Regulates mTOR Signalling and Blocks Cell Proliferation in the Floor Plate 

  Kadoya, Minori; Sasai, Noriaki (Cold Spring Harbor Laboratory, 2019-05-23)

  The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner. The floor plate, located in the ventral-most region of the neural tube, ...
• GPR17 is an essential regulator for the temporal adaptation of Sonic hedgehog signalling in neural tube development 

  Yatsuzuka, Atsuki; Hori, Akiko; Kadoya, Minori; Matsuo-Takasaki, Mami; Kondo, Toru; Sasai, Noriaki (Company of Biologists: Development, 2019-08-23)

  Dorsal-ventral pattern formation of the neural tube is regulated by temporal and spatial activities of extracellular signalling molecules. Sonic hedgehog (Shh) assigns ventral neural subtypes via activation of the Gli ...
• Handheld Guides in Inspection Tasks: Augmented Reality versus Picture 

  Polvi, Jarkko; Taketomi, Takafumi; Moteki, Atsunori; Yoshitake, Toshiyuki; Fukuoka, Toshiyuki; Yamamoto, Goshiro; Sandor, Christian; Kato, Hirokazu (IEEE, 2018-07-01)

  Inspection tasks focus on observation of the environment and are required in many industrial domains. Inspectors usually execute these tasks by using a guide such as a paper manual, and directly observing the environment. ...
• Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system 

  Urasaki, Akihiro; Morishita, Seiya; Naka, Kosuke; Uozumi, Minato; Abe, Kouki; Huang, Liguo; Watase, Emiko; Nakagawa, Osamu; Kawakami, Koichi; Matsui, Takaaki; Bessho, Yasumasa; Inagaki, Naoyuki (Springer Nature, 2019-08-21)

  The zebrafish sensory posterior lateral line is an excellent model system to study collective cell migration and organogenesis. Shootin1 is a cytoplasmic protein involved in neuronal polarization and axon guidance. Previous ...
• Exergame Experience of Young and Old Individuals Under Different Difficulty Adjustment Methods 

  Kaplan, Oral; Yamamoto, Goshiro; Taketomi, Takafumi; Plopski, Alexander; Sandor, Christian; Kato, Hirokazu (MDPI, 2018-11-07)

  In this work, we compare the exergaming experience of young and old individuals under four difficulty adjustment methods. Physical inactivity is a leading cause of numerous health conditions including heart diseases, ...
• Cytokinin Signaling Is Essential for Organ Formation in Marchantia polymorpha 

  Aki, Shiori; Mikami, Tatsuya; Naramoto, Satoshi; Nishihama, Ryuichi; Ishizaki, Kimitsune; Kojima, Mikiko; Takebayashi, Yumiko; Sakakibara, Hitoshi; Kyozuka, Junko; Kohchi, Takayuki; Umeda, Masaaki (Oxford University Press, 2019-05-28)

  Cytokinins are known to regulate various physiological events in plants. Cytokinin signaling is mediated by the phosphorelay system, one of the most ancient mechanisms controlling hormonal pathways in plants. The liverwort ...
• Non-rigid registration of serial section images by blending transforms for 3D reconstruction 

  Funatomi, Takuya; Kubo, Hiroyuki; Mukaigawa, Yasuhiro (Elsevier, 2019-12)

  In this research, we propose a novel registration method for three-dimensional (3D) reconstruction from serial section images. 3D reconstructed data from serial section images provides structural information with high ...
• 原子層制御したシリコン三次元立体表面構造の創製・観察技術 

  Hattori, Ken (公益社団法人 日本表面真空学会, 2019-07-10)

  We have established the original methodology that enable to observe atomic orderings and arrangements of “surfaces with arbitrary directions” on 3D figured structures, by developing diffraction and microscopy techniques. ...
• Enhanced Magneto-Optical Activities of Modulated Fe-Pt Multilayer Metamaterials 

  Hosoito, Nobuyoshi; Yanagi, Hisao (American Physical Society, 2019-06-05)

  We study optical and magneto-optical (MO) properties of epitaxially grown modulated Fe-Pt multilayer metamaterials by means of generalized MO ellipsometry (GME). Large Kerr rotation, ellipticity, and MO coupling parameters ...
• Single-Unit Imaging of Membrane Protein-Embedded Nanodiscs from Two Oriented Sides by High-Speed Atomic Force Microscopy 

  Tanaka, Yoshiki; Tsukazaki, Tomoya (Elsevier, 2019-01-02)
• Structural Basis for the Function of the β-Barrel Assembly-Enhancing Protease BepA 

  Tanaka, Yoshiki; Hayashi, Yugo; Kamikubo, Hironari; Tsukazaki, Tomoya (Elsevier, 2019-02-01)

  The β-barrel assembly machinery (BAM) complex mediates the assembly of β-barrel membrane proteins in the outer membrane. BepA, formerly known as YfgC, interacts with the BAM complex and functions as a protease/chaperone ...
• 2.8-Å crystal structure of Escherichia coli YidC revealing all core regions, including flexible C2 loop 

  Tanaka, Yoshiki; Tsukazaki, Tomoya (Elsevier, 2018-10-20)

  YidC/Alb3/Oxa1 family proteins are involved in the insertion and assembly of membrane proteins. The core five transmembrane regions of YidC, which are conserved in the protein family, form a positively charged cavity open ...
• Shootin1による細胞-基質間の力の発生を介した神経細胞の細胞移動，極性形成，軸索ガイダンスおよびアクチン波 

  稲垣, 直之 (公益社団法人日本生化学会, 2019-04-25)

  Shootin1はクラッチ分子として重合・脱重合を繰り返すアクチン線維と細胞接着分子を連結することで細胞と細胞外基質の間に牽引力を生み出す．さらに，この力の発生はシグナル伝達によって調節を受ける．本稿では，最近のShootin1の解析を通じて明らかとなりつつある神経細胞の極性形成，軸索ガイダンス，細胞移動そして新たな細胞内分子輸送機構アクチン波の分子メカニクスを解説する．
• Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay 

  塚崎, 智也; 田中, 良樹 (Elsevier Inc., 2019-04-23)

  Sarco/endoplasmic reticulum (ER) Ca2+-ATPase 2b (SERCA2b) is a ubiquitously expressed membrane protein that facilitates Ca2+ uptake from the cytosol to the ER. SERCA2b includes a characteristic 11th transmembrane helix ...
• Incident angle and photon energy dependence of polariton lasing in organic microcavity 

  Katsuki, Hiroyuki; Yanagi, Hisao (IOP Publishing, 2019-04-10)

  Organic semiconductor microcavities forming strongly coupled exciton-polaritons are interesting systems due to their nonlinear coherent emission observed even at room temperature. Here, we investigate the incident angle ...

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