• Single-Unit Imaging of Membrane Protein-Embedded Nanodiscs from Two Oriented Sides by High-Speed Atomic Force Microscopy 

  Tanaka, Yoshiki; Tsukazaki, Tomoya (Elsevier, 2019-01-02)
• Structural Basis for the Function of the β-Barrel Assembly-Enhancing Protease BepA 

  Tanaka, Yoshiki; Hayashi, Yugo; Kamikubo, Hironari; Tsukazaki, Tomoya (Elsevier, 2019-02-01)

  The β-barrel assembly machinery (BAM) complex mediates the assembly of β-barrel membrane proteins in the outer membrane. BepA, formerly known as YfgC, interacts with the BAM complex and functions as a protease/chaperone ...
• 2.8-Å crystal structure of Escherichia coli YidC revealing all core regions, including flexible C2 loop 

  Tanaka, Yoshiki; Tsukazaki, Tomoya (Elsevier, 2018-10-20)

  YidC/Alb3/Oxa1 family proteins are involved in the insertion and assembly of membrane proteins. The core five transmembrane regions of YidC, which are conserved in the protein family, form a positively charged cavity open ...
• Shootin1による細胞-基質間の力の発生を介した神経細胞の細胞移動，極性形成，軸索ガイダンスおよびアクチン波 

  稲垣, 直之 (公益社団法人日本生化学会, 2019-04-25)

  Shootin1はクラッチ分子として重合・脱重合を繰り返すアクチン線維と細胞接着分子を連結することで細胞と細胞外基質の間に牽引力を生み出す．さらに，この力の発生はシグナル伝達によって調節を受ける．本稿では，最近のShootin1の解析を通じて明らかとなりつつある神経細胞の極性形成，軸索ガイダンス，細胞移動そして新たな細胞内分子輸送機構アクチン波の分子メカニクスを解説する．
• Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay 

  塚崎, 智也; 田中, 良樹 (Elsevier Inc., 2019-04-23)

  Sarco/endoplasmic reticulum (ER) Ca2+-ATPase 2b (SERCA2b) is a ubiquitously expressed membrane protein that facilitates Ca2+ uptake from the cytosol to the ER. SERCA2b includes a characteristic 11th transmembrane helix ...
• Incident angle and photon energy dependence of polariton lasing in organic microcavity 

  Katsuki, Hiroyuki; Yanagi, Hisao (IOP Publishing, 2019-04-10)

  Organic semiconductor microcavities forming strongly coupled exciton-polaritons are interesting systems due to their nonlinear coherent emission observed even at room temperature. Here, we investigate the incident angle ...
• Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons 

  Huang, Liguo; Urasak, Akihiro; Inagaki, Naoyuki (Springer Nature, 2019-02-12)

  Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the anterograde axonal transport of Golgi-derived vesicles and the ...
• How are IF-Conditional Statements Fixed Through Peer 

  UEDA, Yuki; IHARA, Akinori; ISHIO, Takash; HIRAO, Toshiki; MATSUMOTO, ,Kenichi (The Institute of Electronics, Information and Communication Engineers, 2018-11-01)

  Peer code review is key to ensuring the absence of software defects. To reduce review costs, software developers adopt code convention checking tools that automatically identify maintainability issues in source code. ...
• 車載LANへ侵入するマルウェアの証拠保全を行うカーネル上のフォレンジック機構 

  大平, 修慈; 井上, 博之; 新井, イスマイル; 藤川, 和利 (情報処理学会, 2019-03-15)

  インターネットとつながる自動車において，カーナビ等の車載インフォテインメントシステム（IVI）へのマルウェアの侵入等による車載LANへのサイバー攻撃が問題となっている．また，マルウェアのような不正なプログラムによる事故が発生した場合，ドライバの過失によるものなのか，マルウェアの車載LANへの侵入・攻撃によるものなのかを区別する仕組みはない．不具合や事故が起こった後のデジタル・フォレンジックのためには，その原因となった事象の証拠保全を行う ...
• Syntactic Matching Methods in Pivot Translation 

  Miura, Akiva; Neubig, Graham Pollitt; Sudoh, Katsuhito; Nakamura, Satoshi (言語処理学会, 2018-12-15)

  The pivot translation is useful method for translating between languages that contain little or no parallel data by utilizing equivalents in an intermediate language such as English. Commonly, phrase-based or tree-based ...
• Mode selective excitation of terahertz vibrations in single crystalline rubrene 

  Yano, Keisuke; Katsuki, Hiroyuki; Yanagi, Hisao (American Institute of Physics, 2019-02-06)

  Organic molecular crystals have a variety of low frequency vibrational modes composed of intra- and inter-molecular oscillations. They are mixed intricately in the terahertz (THz) region. We are interested in the controllability ...
• ERK Activity Dynamics during Zebrafish Embryonic Development 

  Wong, Kah-Loon; Akiyama, Ryutaro; Bessho, Yasumasa; Matsui, Takaaki (MDPI, 2018-12-28)

  During vertebrate development, extracellular signal-regulated kinase (ERK) is activated by growth factors such as fibroblast growth factor (FGF), and it regulates the formation of tissues/organs including eyes, brains, ...
• Editorial: Cell Adhesion and Migration in the Development of Multicellular Organisms 

  Takaaki, Matsui (Frontiers, 2018-10-22)
• Noise-resistant developmental reproducibility in vertebrate somite formation 

  Honda, Naoki; Akiyama, Ryutaro; Sari, Dini Wahyu Kartika; Ishii, Shin; Bessho, Yasumasa; Matsui, Takaaki (Public Library of Science, 2019-02-04)

  The reproducibility of embryonic development is remarkable, although molecular processes are intrinsically stochastic at the single-cell level. How the multicellular system resists the inevitable noise to acquire developmental ...
• ランダムフォレストによる路線バス運行状態分類 

  米澤, 拓也; 新井, イスマイル; 秋山, 豊和; 藤川, 和利 (情報処理学会, 2019-02-15)

  バス運行業者が導入しているデジタルタコグラフで記録されている運行・回送・休憩といった車両状態は現状，運転者の手入力に依存しており，運転者の負担が大きい．本研究では，デジタルタコグラフから得られる車速・エンジン回転数や，GPS等から得られるセンサデータを機械学習することで，バスの運行状態の自動分類を試みる．センサデータに加えて，それらを加工して得た，停留所・事業所までの距離等の特徴量をランダムフォレストの入力とする自動分類手法を提案・実装 ...
• Automatic Quantitative Segmentation of Myotubes Reveals Single-cell Dynamics of S6 Kinase Activation 

  Inoue, Haruki; Kunida, Katsuyuki; Matsuda, Naoki; Hoshino, Daisuke; Wada, Takumi; Imamura, Hiromi; Noji, Hiroyuki; Kuroda, Shinya (日本細胞生物学会, 2018-08-31)

  Automatic cell segmentation is a powerful method for quantifying signaling dynamics at single-cell resolution in live cell fluorescence imaging. Segmentation methods for mononuclear and round shape cells have been developed ...
• Chromatin-mediated feed-forward auxin biosynthesis in floral meristem determinacy 

  Yamaguchi, Nobutoshi; Huang, Jiangbo; Tatsumi, Yoshitaka; Abe, Masato; Sugano, Shigeo S.; Kojima, Mikiko; Takebayashi, Yumiko; Kiba, Takatoshi; Yokoyama, Ryusuke; Nishitani, Kazuhiko; Sakakibara, Hitoshi; Ito, Toshiro (Springer Nature, 2018-12-11)

  In flowering plants, the switch from floral stem cell maintenance to gynoecium (female structure) formation is a critical developmental transition for reproductive success. In Arabidopsis thaliana, AGAMOUS (AG) terminates ...
• A cis‐acting bidirectional transcription switch controls sexual dimorphism in the liverwort 

  Hisanaga, Tetsuya; Okahashi, Keitaro; Yamaoka, Shohei; Kajiwara, Tomoaki; Nishihama, Ryuichi; Shimamura, Masaki; Yamato, Katsuyuki T; Bowman, John L; Kohchi, Takayuki; Nakajima, Keiji (EMBO press, 2019-01-04)

  Plant life cycles alternate between haploid gametophytes and diploid sporophytes. While regulatory factors determining male and female sexual morphologies have been identified for sporophytic reproductive organs, such as ...
• Pulsed-laser-activated impulse response encoder (PLAIRE): detection of core–shell structure of biomimetic micro gel-sphere 

  Yasukuni, Ryohei; Minamino, Daiki; Watanabe, Tei; Yamada, Sohei; Iino, Takanori; Bessho, Yasumasa; Matsui, Takaaki; Hosokawa, Yoichiroh (Springer-Verlag GmbH Germany, part of Springer Nature, 2018-08-09)

  Mechanical properties of biological cells and tissues contain important information for further understanding of their function. To estimate mechanical properties of micro-sized biological objects, we developed a system: ...
• Nutrient Signaling via the TORC1-Greatwall-PP2AB55δ Pathway Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae 

  Watanabe, Daisuke; Kajihara, Takuma; Sugimoto, Yukiko; Takagi, Kenichi; Mizuno, Megumi; Zhou, Yan; Chen, Jiawen; Takeda, Kojiro; Tatebe, Hisashi; Shiozaki, Kazuhiro; Nakazawa, Nobushige; Izawa, Shingo; Akao, Takesh; Shimoi, Hitoshi; Maeda, Tatsuya; Takagi, Hiroshi (American Society for Microbiology, 2018-10-19)

  Saccharomyces cerevisiae sake yeast strain Kyokai no. 7 (K7) and its relatives carry a homozygous loss-of-function mutation in the RIM15 gene, which encodes a Greatwall-family protein kinase. Disruption of RIM15 in non-sake ...

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